About The CAR-PSP Project / Clinical research often does not reflect the burden of disease on the population.
Factors like funding sources, vested researcher interests, publication bias, and consumer pressure can influence the research agenda away from the needs of the population it is meant to serve. As a result, questions that patients and clinicians consider important may not be addressed. Ultimately, such bias can negatively impact patient health outcomes. Bringing patients and clinicians together with researchers can prioritize questions, particularly in treatment uncertainty. Additionally, such efforts encourage organizational and institutional collaboration to avoid waste of resources and duplication of effort.
Anesthesia research funding for studies and research trials is generally delivered through ‘responsive funding’ programs in which researchers propose topics to the funding bodies. There is now support,
however, for ‘needs-led’ programs driven by a systematic approach to identifying and setting research and development priorities.
Priority setting partnerships, like those formally facilitated by the James Lind Alliance, provide a valuable opportunity to bring together patients, caregivers, and clinician groups to:
• identify treatment uncertainties (questions about treatments options, methods of care, or
diagnostic tests that cannot be answered by existing research) that are important to all groups;
• work with all groups to jointly prioritize identified uncertainties;
• produce a final list – often a Top 10 – of research priorities; and
• widely publicize priorities.